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Solutions for COVID-19 Therapeutics, Vaccines
and Diagnostics


Repligen is ready to partner to help fast-track the development and manufacturing of your COVID-19 therapeutics, vaccines and diagnostics.

Use our COVID-19 Hotline for accelerated product availability or expert support.

Repligen IS A technology leader in therapeutics production

Rapid response with COVID-19 accelerated lead times

Proven technologies with broad customer base from clinical to commercial = reduced risk

Adoption in diverse platforms including mAbs, proteins, viruses, plasmids, AAV, Lentivirus, mRNA

Providing high impact solutions with priority support

Expert-guided priority support for rapid technology implementation

Leading technologies for upstream process intensification, downstream processing, process analytics - scalable from bench to production scale

Closed, single-use bioprocessing — single-use, Gamma-irradiated, fully integrated flow paths 

Icon_NEW.jpg Protein Ligand for Purification of Covid-19 Vaccines

Repligen and Navigo Proteins develop affinity ligand for the purification of COVID-19 vaccines 

A successful development of an affinity ligand targeting the spike protein, to be utilized in the purification of COVID-19 vaccines, has entered stage two. The program is focused on both scaling up the manufacturing of this ligand, and on the development and validation of the related affinity chromatography resin.

Read More

up to 50% faster lead times for Covid-19 programs 

 Corona Virus 3D.png= Currently used in COVID-19 processes

Upstream Solutions

Downstream Solutions

Time-saving, cost-lowering Solutions

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Needs and Challenges

  • Low shear filtration for pDNA and mRNA purification
  • Closed single-use systems, automated and standardized platforms
  • Demand for manufacturing can be significant so facility thoughput important

Downstream solutions

OPUS® Pre-packed Columns

即取即用,无需装柱经验

Spectrum® Hollow Fiber TFF Filters

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

ProConnex®
流路

Configurable, sterile assemblies, reduced intallation time

KrosFlo® TFF 系统

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

Needs and Challenges

  • High demand biologic - productivity, efficiency, throughput and process economics need to be considered
  • Closed single-use, automated and standardized TFF platforms
  • Scalable chromatography and filtration solutions

Upstream solutions

XCell ATF®
系统

更高的转染前活细胞密度及总衣壳滴度

LONG®R3 IGF-I Growth Factor

200x more potent than insulin

KrosFlo® TFDF® Systems

Combines centrifugation and primary depth filtration, scalable from 1 to 2000L

Downstream solutions

OPUS® Pre-packed Columns

即取即用,无需装柱经验

Spectrum® Hollow Fiber TFF Filters

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

https://www.repligen.com/technologies/pro-connex-flowpaths

ProConnex®
流路

Configurable, sterile assemblies, reduced intallation time

KrosFlo® TFF 系统

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

Needs and Challenges

  • High demand biologic - productivity, efficiency, throughput and process economics need to be considered
  • Closed single-use, low shear, automated and standardized TFF platforms
  • Scalable chromatography and filtration solutions

Upstream solutions

更高的转染前活细胞密度及总衣壳滴度

200x more potent than insulin

KrosFlo® TFDF® Systems

Combines centrifugation and primary depth filtration, scalable from 1 to 2000L

Downstream solutions

即取即用,无需装柱经验

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

ProConnex®
流路

Configurable, sterile assemblies, reduced intallation time

KrosFlo® TFF 系统

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

  • High demand biologic - productivity, efficiency, throughput and process economics need to be considered
  • Closed single-use, low shear, automated and standardized TFF platforms
  • Scalable chromatography and filtration solutions

Upstream solutions

XCell ATF®
系统

更高的转染前活细胞密度及总衣壳滴度

LONG®R3 IGF-I Growth Factor

200x more potent than insulin

KrosFlo® TFDF® Systems

Combines centrifugation and primary depth filtration, scalable from 1 to 2000L

Downstream solutions

OPUS® Pre-packed Columns

即取即用,无需装柱经验

OPUS® Columns with Purolite Protein A Resin

High capacity rPA affinity resin at a fraction of the cost

Spectrum® Hollow Fiber TFF Filters

Low shear TFF,
1400 configurations

SIUS® Gamma
TFF Cassettes

Closed, Gamma-irradiated, no cleaning validation

ProConnex®
流路

Configurable, sterile assemblies, reduced intallation time

KrosFlo® TFF 系统

Fully automated, scalable from bench to production

SoloVPE®
Analytics

No dilution protein quantitation

priority Support available remotely or in person

covid-support.png