HIGH PERFORMANCE

SARS CoV-2 specific affinity resin for the purification of COVID-19 vaccines

 

针对SARS CoV-2刺突蛋白纯化的新型亲和填料,用于疫苗开发和生产

The result of close work with Navigo Proteins on the ligand development and partnership with Purolite Life Sciences on Praesto®agarose bead technology, the new NGL COVID-19 Spike Protein Affinity Resin from Repligen binds the SARS CoV-2 Spike Protein receptor binding domain (RBD) to yield exceptional purity in a single chromatography step. The product meets all the expected requirements of a high-performance resin, including very high selectivity, high dynamic binding capacities and caustic stability over multi-cycle use.

The resin is available in off-the shelf, pre-packed and pre-qualified OPUS® Columns for rapid implementation as well as in loose resin formats.

  HIGH PERFORMANCE

Single-step affinity chromatography with high resolution

NGL COVID-19刺突蛋白亲和填料的主要特点包括:

  • 含有SARS-CoV-2刺突蛋白RBD的产品的单步纯化*
  • 兼容 0.1N NaOH CIP
  • 高结合载量**
* Targets SARs CoV-2 spike protein variants containing the RBD. Examples include: S protein (S1/S2), S1 Protein, RBD, S Protein Trimer. Development data suggest that purification of whole inactivated virus, virus like particles (VLPs), and adenovirus may not yield satisfactory results.
**Actual DBC dependent on S protein variant & size
  HIGH PERFORMANCE

Optimized bead chemistry delivers exceptional purity

NGL COVID-19刺突蛋白亲和填料可在单个纯化步骤中获得>90%的纯度。

以HEK293细胞表达的SARS-CoV-2刺突蛋白受体结合结构域(RBD)以NGL COVID-19刺突蛋白亲和填料纯化的SDS-PAGE凝胶图。

 SPEED TO MARKET

Available pre-packed in OPUS® Columns for quick deployment

 

NGL COVID-19刺突蛋白亲和填料可以经质量确认的现货OPUS® 预装柱形式提供,以简化并加快GMP使用,同时,也提供“散装”填料形式。

使用预装、预质量确认的OPUS®层析柱,可使您在数周内从开发进入生产规模。

OPUS® Pre-packed Columns

Manufacturing Centers of Excellence

Repligen在ISO 9001质量管理体系下开发和生产用于生物制药行业的产品。我们专注于及时交付高质量、一致且稳健的产品,以确保我们客户的业务连续性。

Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands,  Germany and Estonia.

地点

客户至上。

Repligen DNA 为您提供支持。我们的目标是提供卓越的客户体验,并为所有 Repligen 产品和服务高效成功的采用及实施提供支持。

  • Field Application Support
  • 客户服务
  • 现场服务工程师

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