出版物
连续生物工艺：行业最佳实践
电子书，第2册
2018年2月
编辑：John Bonham-Carter，Repligen
章节
- Introduction to Continuous Bioprocessing: Current Status and Trends
Eric S. Langer, BioPlan Associates, Inc. and Ronald A. Rader - How to Develop a Perfusion Process
Véronique Chotteau, Royal Institute of Technology (KTH) - Strategies for development of perfusion media
Delia Lyons, MilliporeSigma and Jochen Sieck, Merck KGaA - Perfusion Application in Mobius® Single-use Bioreactors
Michael Cunningham and Douglas Rank, MIlliporeSigma - XCell ATF® Perfusion Technology Delivers High Throughput: Efficient Seed Train Process with Improved Fed-Batch Production Output
W. Roy Lin, Shashi Kudugunti, Mario Sinani, Tim Erlandson and Dr. James Rusche, Repligen - Product Quality Considerations of Perfusion Processes
Thomas Villiger, Daniel Karst and Massimo Morbidelli, ETH Zurich - Impurity Monitoring as Novel PAT Tool for Continuous Biopharmaceutical Processes
Vignesh Rajamanickam, Dr. Patrick Sagmeister, Oliver Spadiut, and Christoph Herwig, TU Wien Austria - Insect Cells and ATF
Willem Adriaan (Wian) de Jongh, PhD, ExpreS2ion Biotechnologies - Scale up and Technology Transfer in a Continuous Processing Environment
Sadettin S. Ozturk, Ph.D., Massbiologics - Continuous Multicolumn Chromatography Processes
Marc Bisschops, Pall Corporation - Impact of Single‑use Technology on Continuous Bioprocessing
William G. Whitford, GE Healthcare - Continuous Bioprocessing's Impact on Facility Design
Morten Munk, NNE A/S
连续生物工艺：当前实践和未来潜力
电子书，第1册
2014
编辑：John Bonham-Carter，Repligen
章节
- Introduction to Continuous Manufacturing:Technology Landscape and Trends
Eric S. Langer and Ronald A. Rader, BioPlan Associates - A Brief History of Perfusion Biomanufacturing
Jerry Shevitz and John Bonham-Carter, Refine Technology - Bioreactor Configuration and Operation
Christel Fenge, Jörg Weyand, Gerhard Greller, Thorsten Adams, Sartorius Stedim Biotech - How to Develop a Perfusion Process
Véronique Chotteau, Royal Technical University, KTH - Case Study: Optimized Perfusion
Shaun Eckerle, Gallus BioPharmaceuticals - Process Intensification Approaches for Cost Sensitive Protein Applications
Willem Adriaan de Jongh, Expres2ion Biotechnologies - Impact of Single-use Technology on Continuous Biorocessing
William G. Whitford, Thermo Fisher Scientific - Continuous Multicolumn Chromatography Processes
Marc Bisschops, Tarpon Biosystems - Continuous Processes: Economic Evaluation
Andrew Sinclair and Andrew Brown, BioPharm Services - Vision: Integrating Upstream and Downstream in a Fully Continuous Facility
Tim Johnson, Genzyme
技术和应用笔记
数据表
学术海报
白皮书
by David Bianchi, Carl Breuning, Michael LaBreck, Shelly Parra, Mary Jo Wojtusik, Repligen Corporation
Alex Meola, Michael Mercaldi, Thomas Thiers, Homology, Medicines Inc.
Repligen Corporation
Homology, Medicines Inc.
2020年7月
MSD Animal Health 研究 XCell ATF® 灌流技术用于病毒生产工艺强化
Repligen Corporation
MSD Animal Health
7月，2022
Impact of N-1 Seed Train Intensification on Viral Vector Production
by Ly Truong, Riaj Mahamud, Benedict Kang, Keen Chung, Rene Gantier
Repligen Corporation
September 2022
第三方参考文献精选
使用HEK-293生产细胞系和先进灌流工艺生产慢病毒载体
作者：Michelle Yen Tran 和 Amine A. Kamen
Frontiers, 7月 14 日, 2022
Lentiviral vector manufacturing process enchancement utilizing TFDF™ technology
Thomas Williams、Oliver Goodyear、Lee Davies、Carol Knevelman、Michael Bransby、Kyriacos Mitrophanous & James Miskin
Cell and Gene Therapy Insights, 2020年4月
Special Report on Continuous Bioprocessing: Upstream, Downstream, Ready for Prime Time?
Angelo DePalma
BioProcess International， 2016年5月
Continuous Manufacturing: A Changing Processing Paradigm
Randi Hernandez
BioPharm International，2015年4月01日
A Novel Seed-Train Process: Using High-Density Cell Banking, a Disposable Bioreactor, and Perfusion Technologies
Benjamin Wright, Mike Bruninghaus, Mike Vrabel, Jason Walther, Neha Shah, Seul-A Bae, Timothy Johnson, Jin Yin, Weichang Zhou & Konstantin Konstantinov
BioProcess International，2015年3月
Developing an Integrated Continuous Bioprocessing Platform: Interview with Konstantin Konstantinov
Maribel Rios
BioProcess International，2012年12月
A Brief History of Perfusion Biomanufacturing: How High-Concentration Cultures Will Characterize the Factory of the Future
John Bonham-Carter & Jerry Shevitz
BioProcess International，2011年10月