LONG® EGF is a recombinant analog of human epidermal growth factor (EGF) used in regulatory approved cell-based therapies.
growth factor cell culture supplement
LONG® EGF is a recombinant analog of human epidermal growth factor (EGF) used in regulatory approved cell-based therapies. It was developed as a supplement for use in therapeutic cell culture applications as a like-for-like replacement for native EGF or recombinant human EGF (hEGF). The source is a proprietary Escherichia coli fermentation process, manufactured without the use of animal- or human-derived materials.
- GMP compliant in accordance with ICH Q7 guidelines
- Animal-free, proprietary e.coli manufacturing process
- Like-for-like replacement for human, murine or recombinant EGF
- Used in approved and marketed cell-based therapies
Formats
Lyophilized powder dried from 10 mM hydrochloric acid (HCl) in an atmosphere of nitrogen at a slight vacuum (~25 kPa)
- 1 mg
- 20 mg
Storage
- 1 mg: Storage temperature and shipping in cold storage 2-8°C.
- 20 mg: Storage temperature -20°C and shipping in cold storage 2-8°C.
高质量生产
Under a quality management system that is ISO:9001 certified and based on EU GMP
Animal-free
Proprietary e.coli manufacturing process
Synergistic
Positive effects have been observed with LONG®R3 IGF-I in HEK293, MDCK and HeLa cell lines
Wide Range of Applications
LONG® EGF can be used as a supplement for serum-free or low serum culture.
Recombinant LONG® EGF acts via the Erb-1 receptor and has applications in fibroblast cell culture. Synergistic effects have been observed with LONG®R3 IGF-I in HEK293, MDCK and HeLa cell lines.
LONG® EGF is used across a wide range of customer-driven applications, including:
- Therapeutic cell culture in a variety of fibroblast and epithelial cell types
- Keratinocyte differentiation and growth
- Cell-based vaccine production
