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LONG® EGF Cell Culture Supplement


LONG® EGF is a recombinant analog of human epidermal growth factor (EGF) used in regulatory approved cell-based therapies.

growth factor cell culture supplement

LONG® EGF is a recombinant analog of human epidermal growth factor (EGF) used in regulatory approved cell-based therapies. It was developed as a supplement for use in therapeutic cell culture applications as a like-for-like replacement for native EGF or recombinant human EGF (hEGF).  The source is a proprietary Escherichia coli fermentation process, manufactured without the use of animal- or human-derived materials.

  • GMP compliant in accordance with ICH Q7 guidelines
  • Animal-free, proprietary e.coli manufacturing process
  • Like-for-like replacement for human, murine or recombinant EGF
  • Used in approved and marketed cell-based therapies

Formats
Lyophilized powder dried from 10 mM hydrochloric acid (HCl) in an atmosphere of nitrogen at a slight vacuum (~25 kPa)

  • 1 mg
  • 20 mg

Storage

  • 1 mg: Storage temperature and shipping in cold storage 2-8°C.
  • 20 mg: Storage temperature -20°C and shipping in cold storage 2-8°C.
高质量生产

Under a quality management system that is ISO:9001 certified and based on EU GMP

Animal-free

Proprietary e.coli manufacturing process

Synergistic

Positive effects have been observed with LONG®R3 IGF-I in HEK293, MDCK and HeLa cell lines

 

Repligen在ISO 9001质量管理体系下开发和生产用于生物制药行业的产品。我们专注于及时交付高质量、一致且稳健的产品,以确保我们客户的业务连续性。

关于Repligen生产

Wide Range of Applications

LONG® EGF can be used as a supplement for serum-free or low serum culture. 

Recombinant LONG® EGF acts via the Erb-1 receptor and has applications in fibroblast cell culture. Synergistic effects have been observed with LONG®RIGF-I in HEK293, MDCK and HeLa cell lines.

LONG® EGF is used across a wide range of customer-driven applications, including:

  • Therapeutic cell culture in a variety of fibroblast and epithelial cell types
  • Keratinocyte differentiation and growth
  • Cell-based vaccine production
Applications for LONG® EGF