Novel affinity resin for the purification of the SARS CoV-2 Spike Protein for vaccine development and manufacturing
The result of close work with Navigo Proteins on the ligand development and partnership with Purolite Life Sciences on Praesto® agarose bead technology, the new NGL COVID-19 Spike Protein Affinity Resin from Repligen binds the SARS CoV-2 Spike Protein receptor binding domain (RBD) to yield exceptional purity in a single chromatography step. The product meets all the expected requirements of a high-performance resin, including very high selectivity, high dynamic binding capacities and caustic stability over multi-cycle use.
The resin is available in off-the shelf, pre-packed and pre-qualified OPUS® Columns for rapid implementation as well as in loose resin formats.
NGL COVID-19 Spike Protein Affinity Resin key features include:
NGL COVID-19 Spike Protein Affinity Resin delivers >90% purity in one chromatography step.
以HEK293细胞表达的SARS-CoV-2刺突蛋白受体结合结构域(RBD)以NGL COVID-19刺突蛋白亲和填料纯化的SDS-PAGE凝胶图。
NGL COVID-19刺突蛋白亲和填料可以经质量确认的现货OPUS® 预装柱形式提供,以简化并加快GMP使用,同时,也提供“散装”填料形式。
使用预装、预质量确认的OPUS®层析柱,可使您在数周内从开发进入生产规模。