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TangenX™ SIUS™ Gamma Flat Sheet Cassettes

TangenX™ SIUS™ Gamma filtration devices harness the performance and efficiencies of TangenX™ SIUS™ membranes and cassettes with the convenience of a fully assembled, closed and irradiated system.

PERFORMANCE TFF IN A CLOSED DEVICE WITH CONNECTION FREEDOM

TangenX™ SIUS™ Gamma filtration devices harness the performance and efficiencies of TangenX™ SIUS™ membranes and cassettes with the convenience of a fully assembled, closed and irradiated system.

Acclaimed performance with up to a 30% flux increase over conventional membranes, connectivity freedom and a library of molecular weight cutoffs, surface areas, chemistries and screen types converge into one, simple single-use flat-sheet solution. Manufactured under ISO 9001, every unit is integrity tested and quality tested.

Building closed systems can be challenging given the diversity of connectivity options available. TangenX™ SIUS™ Gamma Cassettes make your life easier by giving you connectivity choices. Either configure a ProConnex® flow path based on your specification, select a pre-built ProConnex® flow path that is ready-to-ship or simply plug the filtration device into your existing flow path with genderless AseptiQuik® connectors.

Repligen在ISO 9001质量管理体系下开发和生产用于生物制药行业的产品。我们专注于及时交付高质量、一致且稳健的产品,以确保我们客户的业务连续性。

关于Repligen生产

CLAMP AND GO. IT'S THAT EASY.

The TangenX™ SIUS™ Gamma device arrives as a fully assembled closed device, including cassette, manifold, clamps, tubing and genderless AseptiQuik® connectors. Simply clamp into a holder, make your flow path connections and run your process.

 

 

 

 

Components

  1. Hex nut 
  2. Washer
  3. 3. 2" or 1" tie-rod spacer(s)
  4. Holder top plate
  5. TangenX™ SIUS™ Gamma Cassette
  6. Manifold
  7. Holder bottom plate
Configured for you

Build a specification based flow path from a library of over 400 components with individual quality
testing.

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Compatible
Plug into existing

Leverage the flexibility of genderless connectors and seamlessly connect to your existing flow path.

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Validated for GMP
Ready to Ship

Order a pre-built and quality tested off-the shelf ProConnex® flow path stocked for rapid delivery.

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FIT FOR GENE THERAPY
Ideal for AAV processes where large volumes need to be concentrated 20-60X prior to chromatography
QUALITY MANUFACTURING

Manufactured in compliance with ISO guidelines in an ISO 7 clean room

Defined lead times

全球支持

Work with Repligen Field Applications Specialists from consultation to implementation

Tangenx™ Innovation Inside

 

Diverse options for your diverse process needs

A wide selection of molecular weight cutoffs, surface areas, multiple chemistries and multiple screen types provide you with a library of options to address your diverse process requirements.

From sticky proteins to high concentration samples and from process development to manufacturing, the TangenX™ SIUS™ Gamma provides a closed solution. Scale, solve and move forward with one flat-sheet platform.

Membrane chemistries:

Screens:

 

观看网络研讨会

TangenX™ SIUS™ Gamma TFF cassettes incorporate the performance-leading TangenX™ TFF membrane and cassette manufacturing technologies into a closed, gamma-irradiated, single-use assembly. Genderless, aseptic connections easily integrate into your current UF/DF flow path, and a library of 64 MWCO and surface area configurations provide rich process options.

 

申请报价

Equivalent performance with ready-to-use convenience

 

 

Seamless transition from TangenX™ SIUS™ Flat Sheet Cassette to TangenX™ SIUS™ Gamma Closed TFF Cassette

Process Volume vs. Membrane Area at 200 L/m2 Volumetric Throughput

ProConnex® FLOW PATHS ADD FUNCTIONALITY AND CONVENIENCE

Custom ProConnex® Flow Paths complete your TFF solution

Custom

  • Engineer-designed to customers’ specifications
  • Choose from over 400 components
    • connections
    • process reservoirs
    • pressure transducers
    • aseptic connectors

Quality

  • Individually inspected
  • Integrity testing available
  • Clean room assembled
  • Double-bagged

Bioprocess Grade Materials

  • Class VI
  • BSE/TSE free
  • Lot traceable

Clamp and go

  • Complete flow path or drop-in tube sets

Validated Manufacturing

Quality Manufacturing

TangenX™ Cassettes are manufactured in a fully validated and documented manufacturing process according to the principles of cGMP. Each cassette comes with a Quality Assurance Certificate. 

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Comprehensive Regulatory Support Files

Each TangenX™ TFF Cassette is supported by a Regulatory Support File (available upon request) that includes:

  • Product information
  • Cassette design
  • Materials of construction
  • Product performance
  • Safety information
  • Documentation system
  • Product Manufacturing
  • Qualification
  • Manufacturing Process Validation
  • Release Testing