What's New in Single-use, Continuous and Flexible Bioprocessing Industry case studies

Charles L. Cooney, PhD is the Robert T. Haslam (1911) Professor of Chemical and Biochemical Engineering, Emeritus in the Department of Chemical Engineering at MIT and founding Faculty Director, Emeritus of the Deshpande Center for Technological Innovation. He serves as a consultant to a number of biotech and pharmaceutical companies, and sits on the Boards of Directors of Axcella Health, Boyd Technologies, Codiak Bioscience, GreenLight Bioscience, Innovent Biologics (China), Just Biotherapeutics, LayerBio, Levitronix Technologies, and Mitra Biotech. His research interests include: pharmaceutical manufacturing, bioprocess design, integrated continuous manufacturing and technological innovation strategy.

Nolan Sutherland is a Scientist at bluebird bio. He brings ten years’ experience in Process Development.  Nolan has spent the last five years at bluebird bio where he has worked in the Vector Process Development group focusing on platform design, scaling, and technology transfer of their lentiviral vector manufacturing process.  Currently, Nolan works in bioreactor development evaluating and implementing new enabling technologies and analytics for next generation gene therapy products. Nolan is a graduate of UMass, Amherst with a degree in Biochemistry and Molecular Biology.

John Bonham-Carter is the Director of Upstream Sales at Repligen. John has been a serial entrepreneur with experience in multiple countries in industries from newspapers to biotechnology.  Within bioprocessing, he has worked with many different upstream technologies and, most recently, has propelled the XCell™ ATF System to become the industry leader in continuous culture equipment supply.  John is a regular international speaker on bioprocessing, SME entrepreneurship and business coaching. He is the editor of two eBooks: “Continuous Bioprocessing: Current Practice & Future Potential”  and "Continuous Bioprocessing: Industry Best Practices". John holds a Chemistry Degrees from the University of Bristol.

Mr. Bianchi is currently the Field Applications Specialist for Repligen downstream TFF products. He brings over 20 years of experience in process filtration and separation with a significant portion of that time focused on Tangential Flow Filtration applications utilizing flat sheet cassettes and hollow fiber modules. Mr. Bianchi has held various technical positions supporting Pall Corporation, Spectrum Laboratories, FloDesign Sonics and TangenX™. He holds a Bachelor of Science degree in Chemistry from Worcester Polytechnic Institute.

Justin Crisafulli is currently a Downstream Process Development Scientist at Biogen. Prior to joining Biogen, Justin participated in three process development co-ops at Genzyme, Baxalta, and Momenta While at Northeastern, Justin completed a Bachelor of Science degree in biochemistry as well as three process development co-ops at Genzyme, Baxalta, and Momenta. While at Momenta, he had the opportunity to develop methods on the Tecan Evo system using OPUS®Robocolumns®. This has transferred well in Justin’s transition to Biogen where he is the high throughput process development lead. At Biogen, Justin contributes to the development of monoclonal antibodies and other recombinant proteins. Justin holds a Bachelor of Science degree in Biochemistry from Northeastern University.

Andrew Hedgpeth is an Engineer II working at Biogen in Research Triangle Park, North Carolina. He has spent the majority of his career working in their single-use, GMP facility known a Flexible Volume Manufacturing. While his background is in cell culture and purification of mAbs, he and his team have started purifying antisense oligonucleotides as well. He currently is on a temporary work assignment with the synthesis group for ASOs to learn the upstream processing of the modality. Andrew holds a Bachelor of Science in Chemical Engineering from North Carolina State University.

Fletcher Malcom is a creative MBA graduate and biopharmaceutical industry professional, who spent his early career with Waters Corporation as a technical chromatography representative working with large pharmaceutical and biotechnology clients in the Eastern United States. Since leaving Waters, Fletcher has graduated with honors from Babson’s MBA program, and joined Repligen as a Product and Marketing Manager. In 2011 & 2012 Fletcher led all efforts to complete the development and commercialization of Repligen’s new platform of OPUS® pre-packed disposable columns. Currently, Fletcher is the Director of Product Management for Repligen's Downstream Technologies.