Increase process understanding 

During the process development stage to accelerate product-to-market


Strengthen your process control 

With high quality and highly reproducible results

Reduce cycling time

By eliminating delays associated with off-line testing (yield, throughput, resource utilization)

Minimize risk 

With continuous monitoring throughout the process




We understand your unique research, process development, and manufacturing work requires tailored solutions. That's why we are pleased to offer two light source options for use with the CTech™ FlowVPX® System. The FlowVPX System plays a crucial role in your process optimization and control. It provides real-time results with unprecedented speed, enabling you to gather a greater number of quality data points for higher accuracy compared to off-line methods. The choice of light source allows for further optimization and even stronger process control.

Our compact single-wavelength light source and multiwavelength spectrophotometer are designed to be compatible with the FlowVPX System and interchangeable with one another. This flexibility allows you to scale your project and seamlessly transitions between the two as your proven applications progress towards commercialization. Rest assured that at every stage of your development, we have you covered.

Single Wavelength Light Source: Easy-to-Use GMP Solution


The CTech™ Beams™ single-wavelength LED light source is a reliable and efficient option for applications where a specific wavelength has already been established and proven effective. With a simplified design and user-friendly interface, this light source is perfect for manufacturing biologics, where consistency and precision are crucial. Its benefits include:

  • Proven performance: Designed specifically for established applications at 260 nm or 280 nm, the single-wavelength light source ensures accurate and repeatable measurements that meet the highest industry standards.
  • Easy integration: The compact size of our single-wavelength light source makes it easy to integrate the FlowVPX System into any manufacturing environment without sacrificing valuable space or user-friendliness.
  • GMP-ready design: With an IP65 and C1D2 rating, the FlowVPX System with Beams light source drives towards GMP readiness. The FlowVPX System is available with ViPER SecureVPT Software, specifically designed to support compliance with 21 CFR Part 11. Additionally, for USP/EP/JP compliance, we have mapped out the qualification parallels of the FlowVPX with Beams System to the industry standards in our technical note:CTech Beams System Qualification and Pharmacopeia Compliance.

The CTech Beams LED light source is a single-beam instrument that delivers precise and concentrated light and is ideal for wavelength-specific applications. It comes in 260 nm, 272 nm, 280 nm, and 310 nm as single wavelengths.

Multiwavelength Spectrophotometer: Empowering Process Development


The Cary 60 UV-Vis spectrophotometer is a double-beam instrument with a powerful xenon lamp. It has a wavelength range of 190–1100 nm that can be scanned in under three seconds.

For applications that demand versatility and flexibility, the FlowVPX System connected with the Agilent Cary 60 UV-Vis spectrophotometer offers a wide range of capabilities. It is the perfect choice for process development, research laboratories, and industries exploring more efficient avenues for concentration determination in real time. Here's why you should consider our multiwavelength spectrophotometer:

  • Broad wavelength range: Our multiwavelength spectrophotometer allows you to analyze a wide range of wavelengths (190 nm to 1100 nm), empowering you to explore different applications and adapt to evolving research needs.
  • Research-driven flexibility: The multiwavelength spectrophotometer gives you the freedom to customize experiments, optimize processes, and delve into new research areas, unlocking endless possibilities.

Complete Confidence Regardless of Your Choice


We recognize that your needs are unique. Whether you require a compact, single-wavelength light source for proven applications or a multiwavelength spectrophotometer for process development, we have the solution that best suits you.

During testing, we evaluated the FlowVPX System with Cary 60 and FlowVPX System with Beams light source, focusing on high concentrations and conditions where concentrations change rapidly.

Time (minutes) FlowVPX with Beams In-line Concentration (mg/ml) FlowVPX with Cary 60 In-line Concentration (mg/ml) SoloVPE At-line Concentration (mg/ml)
0.00 6.23 6.27 6.24


11.56 11.18 11.05
22.80 20.08 21.03 20.98
57.40 107.19 111.93 112.18
64.90 135.97 129.79 130.14
73.00 158.32 152.44 158.58

Comparability was demonstrated between the FlowVPX System using the Beams light source and the FlowVPX System using the Cary 60 as its light source. Findings revealed that both systems yield highly consistent results when compared to the at-line CTech™ SoloVPE® System.

Here we demonstrate the real-time concentration readings achieved by FlowVPX with Beams, showcasing the similarity to data obtained using FlowVPX with Cary 60, and finally compared to the at-line SoloVPE System, spanning a broad concentration range from 6 mg/ml to nearly 160 mg/ml of a monoclonal antibody.

Our data showcases the VPT platform's consistent, accurate, and reproducible results, regardless of the light source or placement (in-line/at-line). The VPT platform is the ideal choice to fulfill all your UV-Vis spectroscopy requirements from development to manufacturing.



Compliance Software ViPER ANLYTX Security License Software v1.2 and newer
连接性 USB
Control Software ViPER ANLYTX Software v1.2 and newer
Cannister Dimensions (D x H) 2.5 x 7.1 cm (1 x 2.8 in)
Cannister Weight 0.2 kg (0.4 lb)
Controller Dimensions (D x H) 10.4 x 16 x 6.1 cm (4.1 x 6.3 x 2.4 in)
Controller Weight 1.3 kg (3 lb)
Light Source Single-wavelength LED
Photometric System Single Beam
Power Requirements 100-240V, 47-63 Hz. Beams Controller provides FlowVPX head and detector (Power to Head connection) 24V DC, 1A max.
Wavelength Selection of 260 nm, 272 nm, 280 nm, or 310 nm
Body Construction 316L Stainless Steel



Compliance Software Cary WinUV Pharma
连接性 USB
Control Software Cary WinUV for UV-Vis Applications
Dimensions (W x D x H) 477 x 567 x 196 cm (19 x 22 x 8 in)
Light Source Xenon flash lamp (80 Hz)
Maximum Scanning Speed UV-Vis 24,000 nm/min
Photometric System Dual Beam
Power Requirements 100-240 VAC, 50/60 Hz
Wavelength 190 - 1100 nm
重量 18.1 kg (40 lbs)
Body Construction Plastic
Body Construction 316L Stainless Steel
FlowVPX Applications

Cary 60

CTech Beams System

Culture density

Plasmid concentration

Plasmid purity

DNA/RNA concentration

DNA/protein purity

DNA/salts + solvents purity

Dynamic binding capacity

Continuous chromatography

Viral titer

UF/DF monitoring

Drug product formulation

Operating System: Windows 10 compatible

Software Environment:

  • Beams light source: ViPER® v1.2 or newer when using Beams light source
  • Cary 60 light source: Agilent WinUV Software Suite v5.1.0.1019 or newer

Required Computer Hardware: 

  • Min Processor: Intel i5 (i7 preferred)
  • Min Hard drive: 250 GB (SSD preferred) 
  • Min RAM: 8 GB (16 GB preferred)

Support Services

Enjoy the benefit of year-round technical support, scheduled maintenance, and more. We offer one- to three-year service contracts for your FlowVPX System. Schedule a visit from a Repligen analytical representative to qualify your FlowVPX System.

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Application Services

Supplementary to our standard support options, application services provide you with increased access to our highly knowledgeable and experienced professionals. We offer implementation, method development, and educational guidance to maximize the benefits of your variable pathlength solutions and the Slope Spectroscopy® technique. 

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