MAXIMIZED PERFORMANCE

Gentle on shear-sensitive molecules

Hollow fibers possess a smooth internal wall and tubular channel geometry, that promotes laminar flow with high flux. The low shear and turbulence of laminar flow helps maintain the integrity of shear sensitive modalities such as lentivirus.

Laminar flow

Flow is primarily straight and streamlined

 

Turbulent flow

Irregular, chaotic flow creates eddies that change flow in both magnitude and direction

膜应用

下表所示为不同膜材质过滤器的典型应用

应用 膜选择 mPES PES ME PS
Concentration and diafiltration (buffer exchange) of proteins, peptides, enzymes, recombinant proteins 3, 5, 10, 30, 50, 70,100kD x x
水 / 缓冲液除热源 3, 10kD x x
纳米颗粒包被、洗滤、分馏和/或脱水 70,100,300,500,750kD, 0.2µm x x
白蛋白(标称分子量67kd)浓缩和洗滤 10kD x
单克隆抗体(155kd)浓缩和洗滤 30kD x
有囊膜和无囊膜病毒浓缩和洗滤 50, 70, 100, 300, 500, 750kD, 0.05µm x x
细胞裂解液、表达病毒的培养液澄清,回收滤液中的产物 500, 750kD, 0.05, 0.1µm x x x
Concentration and washing of insect, bacterial and/or mammalian cells 750kD, 0.1, 0.2, 0.5, 0.65µm x x x
生物反应器连续细胞灌流培养 30, 50, 70, 100, 300, 500, 750kD, 0.2, 0.65µm x x
单链或双链核酸浓缩和洗滤 3, 5, 10, 30, 50, 70,100kD x
Washing latex, polystyrene and other diagnostic particles to remove un-reactives / unbound drug substance 500, 750kD, 0.05, 0.1, 0.2, 0.65µm x x x

配置器

Find a Spectrum Hollow Fiber Filter

Search for Spectrum Hollow Fiber Filters by Module Family, Membrane Chemistry, MWCO, and other parameters.

Hollow Fiber Calculator

Easy-to-use online Hollow Fiber Filter tool for calculating critical process parameters like Flow Rate Per Fiber, Holdup Volume, Total Surface Area, and more.

产品编号规则

To specify the hollow fiber filter specific to your application, follow the product number key below.

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