OPUS® MiniChrom® Pre-packed Columns
LEADER OF THE PACK
Designed for bench-scale resin screening, process development, and sample preparation, OPUS® MiniChrom® Columns are pre-packed with user-specified resin and supplied ready to use with any liquid chromatography system. Flexible column dimension configurations (internal diameters, bed heights, volumes) allow comparative evaluation of process parameters and the construction of customized resin libraries.
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无可比拟的灵活性
Pre-packed Packed with any user-specified process resin
Compatible with any liquid chromatography system
内径、柱床高度和层析柱体积规格可根据特定的工艺开发需求进行定制
宽泛的可放大性
可达 10 ml 体积和 3 种直径
高性能
工艺填料批次间的可靠性能
小体积规格可降低对物料的需求，并节省宝贵的填料样品，同时获得与更大的制备型或工艺层析柱相似的性能
Click and quote OPUS® PD Pre-packed chromatography columns
Configure and quote pre-packed columns using the latest web-based technology.
When you are planning your next set of small-scale chromatography experiments, configure the columns online and obtain a quote in minutes. Simply login, select your format, volume and resin that meets your experimental design and add to cart. A quote with all details and pricing will be emailed to you within minutes.
Make your chromatography life easier.
Ultimate Flexibility
Any resin, multiple column dimensions
Currently platformed in various process development projects, as well as for resin sampling by various resin vendors, over 30,000 OPUS® MiniChrom® Columns have been in used in the industry since 2007. Individual laser labeling containing Part Number and Serial Number ensure traceability to the corresponding performance data.
- Pre-packed with over 200 user-specified chromatography resins
- 8 种不同层析柱直径
- 明确定义且文件记录的装柱程序以及正确的压缩系数，可实现工艺填料的高性能
- 折合HETP一致接近5
- 不对称性稳定为1.1 - 1.2
- 高达30 bar的耐压性
- 与所有常见的液体层析系统兼容 - 1/16" 母鲁尔接头
- Available Certificate of Analysis (CoA) for each individual column
可选构型
内径 |
柱床高度 |
柱体积 |
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| cm | mm | cm | mm | mL |
| 0.5 | 5.0 | 1.0 | 10.0 | 0.2 |
| 0.5 | 5.0 | 2.5 | 25.0 | 0.5 |
| 0.5 | 5.0 | 5.0 | 50.0 | 1.0 |
| 0.8 | 8.0 | 2.0 | 20.0 | 1.0 |
| 0.8 | 8.0 | 5.0 | 50.0 | 2.5 |
| 0.8 | 8.0 | 10.0 | 100.0 | 5.0 |
| 1.13 | 11.3 | 5.0 | 50.0 | 5.0 |
| 1.13 | 11.3 | 10.0 | 100.0 | 10.0 |
Rapid and simple AAV capture and polish DOE with new digital tools
This outline describes the advanced and fully automated purification development and optimization for an AAV vector with OPUS® RoboColumns® and Tecan’s Fluent™ robotic workstation.
High Performance
工艺开发
- 填料筛选 / 条件筛选
- 参数优化
用于特定分子的纯化工作流的开发需要针对每一个层析步骤进行填料和操作条件评估。
使用规模缩小的层析柱配置可提高效率和通量。OPUS® MiniChrom®层析柱的性能与更大规模层析柱的性能相当，从而获得可靠且可预测的层析性能数据。使用这些小体积的规模缩小层析柱进行工艺开发，可节省宝贵的样品、成本、资源和时间。
结果可以保存在首选填料的填料库中。
High Performance
样品制备 / 过程分析技术 (PAT)
- 更大的蛋白质数量
The development and manufacture of a biotherapeutic requires significant analytical characterization of in-process intermediates. Non-purified samples require sample preparation before analysis can be executed. OPUS MiniChrom Columns enable one-step purification of multiple samples in parallel.
Use of OPUS MiniChrom Columns generates 8-400 mg of sample per run.
OPUS MiniChrom Pre-packed Columns for Process Development
Designed for bench-scale resin screening, process development, and sample preparation, OPUS® MiniChrom® Columns are pre-packed with user-specified resin and supplied ready to use with any liquid chromatography system. Flexible column dimension configurations (internal diameters, bed heights, volumes) allow comparative evaluation of process parameters and the construction of customized resin libraries.
OPUS® RoboColumn® Pre-packed Columns
LEADER OF THE PACK
OPUS® RoboColumn® miniaturized pre-packed columns are designed for automated chromatography process development and sample preparation using robotic liquid handling workstations.
OPUS® ValiChrom® Pre-packed Columns
LEADER OF THE PACK
OPUS® ValiChrom® Columns are glass pre-packed columns that are exact scale-down models of full-scale columns, ideal for process validation, including virus clearance studies.
客户至上。
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- Field Application Support
- 客户服务
- 现场服务工程师
规格
|
柱内径 |
5 mm |
8 mm |
11.3 mm | |||||
|
装填柱床高度 |
10 mm |
25 mm |
50 mm |
20 mm |
50 mm |
100 mm |
50 mm |
100 mm |
|
柱体积 |
0.2 mL |
0.5 mL |
1.0 mL |
1.0 mL |
2.5 mL |
5.0 mL |
5.0 mL |
10.0 mL |
|
内截面积 |
0.2 cm2 |
0.5 cm2 |
1.0 cm2 |
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|
接头 |
手紧接头 1/16"，母鲁尔 (10-32) |
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|
柱材料 |
聚丙烯 |
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化学稳定性 |
所有常用水性缓冲液，pH 1 – 14，有机溶剂**。 |
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柱储存溶液 |
AIEC 和 CIEC 层析柱： 20 %乙醇 + 150 mM 氯化钠 |
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推荐 储存温度 |
AIEC、CIEC、HIC、SEC 和 MMC：+4°C - +30°C |
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工作温度 |
+4°C - +30°C |
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最高工作 压力 |
最高30bar |
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流速 |
16 – 1000 cm/h** |
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标签 |
激光印刻在每根层析柱柱体上。标签包含：
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* 还需要考虑所预装的层析填料的化学稳定性。更多信息，请参考厂商的填料规格说明。