XCell® ATF 系统

SIMPLIFY AND INTENSIFY

XCell® ATF Systems attach to a bioreactor to intensify upstream manufacturing capacity, productivity, and throughput.

Why It Matters 关于 The R Factor 资源

申请报价

Intensification leader

Increased throughput

10X VCD and lower COGS

Breakthrough technology

Innovative ATF technology

整合式系统

Intensification Leader

Intensification delivers more product faster

XCell^® ATF Technology helps simplify and intensify upstream processes to deliver more product, faster. Intensified processes achieve higher cell densities, require smaller bioreactors and consume less suite time. Increase throughput, productivity, and capacity in both clinical and commercial manufacturing.

Breakthrough technology

How XCell® ATF Technology Works

The XCell^® ATF System is based on award-winning alternating tangential flow (ATF) technology, created by the action of a diaphragm moving upward and downward within a pump head, connected to a filter housing and attached to a bioreactor. Alternating tangential flow is attained by the action of a diaphragm pump.

Breakthrough technology

Ready to scale from process development to manufacturing

The XCell^® ATF System simplifies and fast-tracks upstream intensification development from PD to commercial scale. Intensification increases throughput, accelerates tech transfer and optimizes your process in clinical manufacturing and MSAT while increasing bioreactor productivity and reducing costs in commercial manufacturing. Higher productivity, smaller bioreactors and higher throughput with shorter times to harvest, combine to mitigate facility expansion risks and capital costs.

整合式系统

Design simplicity with XCell™ Lab System

Designed and engineered as a complete solution, the XCell™ Lab System integrates a modern controller, XCell® ATF Devices, software and flow sensors into a complete solution.

精确工程设计的控制器，促进工艺强化
Configurable set-up delivers high throughput - a single manifold supports up to 8 XCell® ATF Devices
软件通过用户友好的界面，实现精确的技术控制
New XCell ATF® 1 Device is fit for low volume intensification ready for scale-up
Repligen 全球技术支持可确保成功的技术实施和规模放大

XCell™ Lab 系统

XCell^® ATF Devices and Controllers

The XCell ATF System delivers a complete solution for upstream intensification with robust hardware software integration. Available in single-use and stainless steel formats with sizes from lab-scale (2 L) to process scale (5000 L). Each system consists of an XCell ATF^® Device, XCell™ Controller, software, tubing and sensors.

设备规模

设备形式

控制器

XCell^{^®} ATF Systems

XCell^® ATFCell retention technology simplifies and fast-tracks upstream intensification development for gene therapy, fed-batch intensification, seed train intensification, perfusion, and media exchange applications.

基因治疗

Emerging modalities

灌流

N-1 灌流

种子扩增强化

The XCell™ Lab Controller solves your productivity puzzle with new engineering, increased throughput and more process data. Turn the frustration of endless permutations into a simple solution that generates more cells, and more product…faster.

Think outside the blocks

Intensification is worth it. Build an intensified upstream suite brick by brick with XCell ATF® systems. Make twice as much product in half the time as you watch VCD grow and shrink bioreactor sizes within the same facility footprint.

OMW! with XCell™

OMG life gets busy. Set-up industry-best cell culture intensification in less than 30 minutes with the design simplicity of XCell ATF® devices. Celebrate more product at work…and still have time for the special moments at home. YGTI.

RGEN

Manufacturing Centers of Excellence

Repligen在ISO 9001质量管理体系下开发和生产用于生物制药行业的产品。我们专注于及时交付高质量、一致且稳健的产品，以确保我们客户的业务连续性。

Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands, Germany, France and Estonia.

地点