KrosFlo® RS TFF Systems
WHEN EVERY DROP COUNTS
Ideal for mRNA and gene therapy solutions, KrosFlo® RS TFF Systems are engineered for maximum recovery. The combination of injection molded tubing, over-molded connections, and valve blocks significantly lowers hold-up volume.
WHEN EVERY DROP COUNTS
For mRNA, AAV, Lentivirus developers
通过创新阀组技术，实现残留体积最小化
Intelligent mixing even at the lowest working volume
READY TO SCALE FAST
For effortless scaling from 1/4" to 1"
Maintain processes while scaling to production
当每一滴都至关重要
通过创新阀组技术，实现残留体积最小化
Ideal for mRNA and gene therapy solutions, KrosFlo® RS TFF Systems are engineered for maximum recovery.
注塑成型管路、超模塑连接和阀组的结合可显著降低残留体积。
当每一滴都至关重要
Intelligent mixing even at the lowest working volume
Innovative tulip tank technology delivers hold-up volumes as low as 1.5L with active mixing.
As fluid levels drop, the dual impellers independently adjust speed to reduce harmful surface interaction while automated valves adapt retentate flow to avoid damage upon entering the tank.
Tulip Tank cart available with KrosFlo® RS 30, 40, 50
ZERO MANUAL INTERVENTION
通过“端到端”的自动化，消除批间差
从开始到结束，完全自动化的工艺，消除干扰
Traditional single-use systems require manual manipulation due to the limited number of controlled valves. Additional controlled valves throughout the flowpath allow complete automation of processes.
消毒
- WFI/缓冲液冲洗
- 完整性检测
浓缩
- 补料分批浓缩
- 批次浓缩
收获
- Product Recovery
- 在线清洗
READY TO SCALE FAST
Maintain processes while scaling to production
KrosFlo® RS 20
0.1 - 0.5 m²
KrosFlo® RS 30
0.5 - 3 m²
KrosFlo® RS 40
1 – 5 m²
KrosFlo® RS 50
5 – 10 m²
Industrial grade components and extended automation allow for confident process scaling. With the same software, hardware, controls and cGMP compliance built into every system, process change challenges in scale-up are removed.
KrosFlo® RS TFF Systems
KrosFlo® RS Single-use Tangential Flow Filtration (TFF) Systems incorporate the most advanced engineering principles to achieve unprecedented automation, hold-up volume and process control. The unique tulip tank continuously measures sample volume and then adjusts dual impeller speeds and retentate routing to nearly eliminate foaming. Conceptualized as a platform, rather than a single system, a single architectural approachenables effortless scale-up from 1/4" to 1".
Click on the tabs to explore features of the different KrosFlo RS Systems.
KrosFlo® RS 20 TFF System
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KrosFlo® RS 30 TFF System
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KrosFlo® RS 40 TFF System
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KrosFlo® RS 50 TFF System
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Error-free installation in minutes with pre-assembled flow paths
ProConnex Flow Paths, pre-assembled and specific to the KrosFlo® RS TFF System, are intuitively designed for simple, mistake-free installation. All system sensors are pre-calibrated and assembly is done in minutes with no confusing instructions.
Click on the left/right arrows or swipe to see flow path assembly steps for the different KrosFlo® RS TFF Systems.
Expert Project Management
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