Go with the Flow II: Automation of biologics drug product manufacturing through modeling and FlowVPE
The presentation will focus on the development, testing, and justification of an advanced control strategy for automating the dilution process during the formulation step in fill-finish manufacturing. The proposed control strategy is founded on precise, accurate and fast protein concentration measurements, all provided by the FlowVPE technology. Being able to rely on timely, high-quality concentration measurements, the novel strategy combines the FlowVPE implemented on-line with real-time data processing and modelling, to achieve immediate feedback control of the dilution process without the need for human intervention. Speakers: Janssen-Renata Pocitarenco; Marius Mueller