Dare to Innovate Across the Workflow

Rediscover the latest bioprocessing innovations, presentations, and scientific posters unveiled during our 2024 tradeshows. Insights for intensifying your cell culture, optimizing your process development, and accelerating your speed to the market are available throughout.

Reducing risk in bioprocess manufacturing through innovation

Minimizing risk is paramount to ensure process efficiency and integrity of biotherapeutics. This talk dives into:

• How risk mitigation can be achieved throughout your manufacturing process with the latest innovations in bioprocessing
• Benefits of adopting single-use technologies to reduce contamination risk 
• Proactive risk management through end-to-end automation and continuous monitoring     

Intensified Production of Recombinant Vesicular Stomatitis Virus-Based Vectors by Tangential Flow Depth Filtration

This video and poster covers a study that explores the transformative potential of a TFDF perfusion system for upstream bioprocessing. You'll learn:

• How viral vector production using a TFDF perfusion system can result in a 460% increase in space-time yield 
• How using a TFDF system can allow continuous virus harvesting and clarification in one step
• The great potential of the TFDF perfusion system towards the establishment of intensified vector production

Latest Innovations

KrosFlo RS 10 TFF System

The first automated, bench-scale TFF system built specifically for cGMP production. The KrosFlo RS 10 tubing is an 1/8th-inch inner diameter and features the same components, controls, and capabilities as a large-scale TFF system used in commercial manufacturing. This includes all the valves, inlets, and outlets for complete end-to-end automation of the entire TFF process, such as buffer and caustic flushing, integrity and permeability testing, ultrafiltration and diafiltration (UF/DF), and product recovery.

TangenX^® SC 

The TangenX^® SC is a self-contained, single-use device featuring a true flat sheet design that is gamma sterilized. With no need for a holder or torquing, it helps users eliminate product loss risk, reduce set-up time by 80%, and eliminate decommission time, thereby enhancing facility efficiency.

ProConnex^® MixOne Carboy System

For those high-value bioprocess drug products where superior mixing, secure storage, or safe transportation of pharmaceutical products is critical, the ProConnex^® MixOne Carboy system offers industry leading mixing technology, Truelev, integrated into a secure single-use rigid carboy which can be easily and safely transported in the ProConnex^® MixOne Secure Carrier. 

ProConnex^® RG-V film 

Repligen ProConnex^® RG-V Film is a state-of-the-art film developed specifically to meet the stringent quality standards of upstream and downstream single-use bioprocessing applications. Used to manufacture standard and custom 2D and 3D bag assemblies, this film offers superior leak and puncture resistance, excellent flex crack resistance, and optimal gas and water vapor barrier properties.