ZERO MANUAL INTERVENTION

Automate from sanitization to recovery 

通过“端到端”的自动化,消除批间差

READY TO SCALE FAST

For effortless scaling from 1/4" to 1"

Maintain processes while scaling to production
当每一滴都至关重要

通过创新阀组技术,实现残留体积最小化

Ideal for mRNA and gene therapy solutions, KrosFlo® RS TFF Systems are engineered for maximum recovery.

注塑成型管路、超模塑连接和阀组的结合可显著降低残留体积。

当每一滴都至关重要

Intelligent mixing even at the lowest working volume

Innovative tulip tank technology delivers hold-up volumes as low as 1.5L with active mixing.

As fluid levels drop, the dual impellers independently adjust speed to reduce harmful surface interaction while automated valves adapt retentate flow to avoid damage upon entering the tank.​

Tulip Tank cart available with KrosFlo® RS 30, 40, 50

ZERO MANUAL INTERVENTION

通过“端到端”的自动化,消除批间差

从开始到结束,完全自动化的工艺,消除干扰

Traditional single-use systems require manual manipulation due to the limited number of controlled valves. Additional controlled valves throughout the flowpath allow complete automation of processes.

消毒​

  • WFI/缓冲液冲洗​
  • 完整性检测

浓缩

  • 补料分批浓缩
  • 批次浓缩

收获

  • Product Recovery​
  • 在线清洗
READY TO SCALE FAST

Maintain processes while scaling to production

KrosFlo® RS 20​
0.1 - 0.5 m²

KrosFlo® RS 30​
0.5 - 3 m² 

KrosFlo® RS 40​
1 – 5 m² 

KrosFlo® RS 50​
5 – 10 m² 

Industrial grade components and extended automation allow for confident process scaling. With the same software, hardware, controls and cGMP compliance built into every system, process change challenges in scale-up are removed.

KrosFlo® RS TFF Systems

KrosFlo® RS Single-use Tangential Flow Filtration (TFF) Systems incorporate the most advanced engineering principles to achieve unprecedented automation, hold-up volume and process control. The unique tulip tank continuously measures sample volume and then adjusts dual impeller speeds and retentate routing to nearly eliminate foaming. Conceptualized as a platform, rather than a single system, a single architectural approachenables effortless scale-up from 1/4" to 1".

Click on the tabs to explore features of the different KrosFlo RS Systems.

KrosFlo® RS 20 TFF System

Click on the links to explore different features.

KrosFlo® RS 30 TFF System

Click on the links to explore different features.

KrosFlo® RS 40 TFF System

Click on the links to explore different features.

KrosFlo® RS 50 TFF System

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Error-free installation in minutes with pre-assembled flow paths

ProConnex Flow Paths, pre-assembled and specific to the KrosFlo® RS TFF System, are intuitively designed for simple, mistake-free installation. All system sensors are pre-calibrated and assembly is done in minutes with no confusing instructions.

Click on the left/right arrows or swipe to see flow path assembly steps for the different KrosFlo® RS TFF Systems.

 

 

 

The world's most advanced TFF systems

In an era of new modalities, developers are striving to maximize efficiency.

The new KrosFlo® RS TFF systems by Repligen empower users through maximized recovery, full automation and effortless scaling.

Read Why

Manufacturing Centers of Excellence

Repligen在ISO 9001质量管理体系下开发和生产用于生物制药行业的产品。我们专注于及时交付高质量、一致且稳健的产品,以确保我们客户的业务连续性。

Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands,  Germany and Estonia.

地点

Expert Project Management

客户至上。

Repligen DNA 为您提供支持。我们的目标是提供卓越的客户体验,并为所有 Repligen 产品和服务高效成功的采用及实施提供支持。

  • Field Application Support
  • 客户服务
  • 现场服务工程师

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